Research & Future Tech
Non-invasive monitoring, AI/ML applications, and emerging CGM technologies
Implantable Long-Term CGM Solutions
Implantable long-term CGM systems place a glucose sensor fully under the skin, and the current Eversense 365 is labeled for up to 1 year of wear. We e...
Interoperability with Automated Insulin Delivery (AID)
How continuous glucose monitors (CGMs) achieve interoperability with automated insulin delivery (AID) systems through the FDA's separate iCGM, ACE pum...
Regulatory Pathways for Non-Invasive Devices
How the FDA classifies non-invasive continuous glucose monitoring devices and which regulatory pathways (510(k), De Novo or PMA) apply. As of October ...
Optical and Fluorescence-Based Glucose Transduction
Optical and fluorescence-based glucose transduction measures glucose with light instead of an electrical current. We explain how the fluorescent senso...
Optical and Spectroscopic Glucose Sensing
How optical and spectroscopic glucose sensing works, from near-infrared, mid-infrared and Raman spectroscopy to the fluorescence chemistry of the impl...
Smart Contact Lenses & Tear Glucose
Smart contact lenses that read glucose in tears are still a research idea: the best-known effort, the Google (later Verily) and Alcon glucose lens, wa...
Dual-Hormone AID Systems
Dual-hormone AID systems add glucagon to automated insulin delivery so the system can push glucose up as well as down. As of October 2026 the bihormon...
Microneedle Array Geometries for CGMs
Microneedle array geometries for continuous glucose monitoring (CGMs): how needle length, tip sharpness, spacing, needle count and material affect ins...
Non-Invasive Glucose Monitoring Technology
Non-invasive glucose monitoring technology aims to measure glucose without piercing the skin, and as of October 2026 the FDA has not authorized any sm...
Sensor Fusion in Automated Insulin Delivery (AID)
Sensor fusion in automated insulin delivery (AID) combines several measurements into one estimate the dosing algorithm can act on. This article explai...
Sweat-based Glucose Sensing and Microfluidics
Sweat-based glucose sensing uses wearable microfluidic patches to measure the small amount of glucose in sweat. As of October 2026 it is still a resea...
Biofuel Cell CGMs
Biofuel cell CGMs are experimental continuous glucose monitors that would draw their power from the glucose they measure. We explain how the chemistry...
Enzymatic Biofuel Cells for Self-Powered Sensors
Enzymatic biofuel cells turn glucose into electricity, which could let self-powered sensors read glucose from the same reaction that powers them. As o...
Multi-Analyte Sensing in CGMs
Multi-analyte sensing in CGMs means one wearable sensor measuring glucose plus another analyte, such as ketones or lactate. This article explains how ...