Sensor Bio-fouling and Biocompatibility in Continuous [Glucose Monitoring](/)

Introduction

Continuous glucose monitoring (CGM) systems have revolutionized the management of diabetes by providing real-time glucose level data. However, one of the significant challenges faced by these systems is sensor bio-fouling and biocompatibility issues.

Bio-fouling

Bio-fouling refers to the accumulation of biological material, such as proteins, cells, and other substances, on the surface of the sensor [1]. This can lead to a decrease in sensor accuracy and longevity.

Biocompatibility

Biocompatibility is the ability of the sensor material to be compatible with the body's tissues, without causing any adverse reactions [2].

Impact on CGM Systems

Sensor bio-fouling and biocompatibility issues can significantly impact the performance and reliability of CGM systems.

Manufacturers' Approaches

Several manufacturers, including Dexcom, Medtronic, and Abbott, are working to address these issues through the development of new materials and technologies [3].

Future Directions

Further research is needed to develop sensors with improved biocompatibility and resistance to bio-fouling.