Technology & Innovation

Multi-Analyte Test Strips (Glucose + Ketone)

Multi-analyte test strips have evolved to measure β-hydroxybutyrate (β-HB) alongside glucose, addressing the critical need for early Diabetic Ketoacidosis (DKA) detection. Unlike urine strips that measure acetoacetate (a lagging indicator), electrochemical blood strips utilize the enzyme β-Hydroxybutyrate Dehydrogenase (β-HBDH) and the cofactor NAD+ to quantify β-HB, the primary ketone body present during DKA.

The market is bifurcated into a medical sector (Abbott, Nova Biomedical) focused on T1D safety and hospital accuracy, and a consumer sector (Keto-Mojo, ForaCare) driven by the ketogenic diet trend. Technological advancements have moved from dual-port meters to single-port devices that auto-detect strip types, with advanced error-correction for hematocrit variance. The future of this technology lies in the integration of ketone sensing into Continuous Glucose Monitors (CGM), creating dual-analyte continuous sensors.

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Introduction to Multi-Analyte [Test Strips](/sell-diabetic-supplies)

Meet the game-changer in blood glucose monitoring: multi-analyte test strips! They detect β-hydroxybutyrate (β-HB), a key indicator of Diabetic Ketoacidosis (DKA).

How it Works

These strips use β-Hydroxybutyrate Dehydrogenase (β-HBDH) and NAD+ to quantify β-HB. This beats urine strips, which measure acetoacetate, a lagging indicator.

Market Overview

The market splits into two sectors:

  • Medical: Companies like Abbott and Nova Biomedical focus on Type 1 Diabetes (T1D) safety and hospital accuracy.
  • Consumer: Companies like Keto-Mojo and ForaCare cater to the growing demand from the ketogenic diet trend.

Technological Advancements

Technology advances have led to:

  • Single-port devices that auto-detect strip types
  • Advanced error-correction for hematocrit variance

Future Developments

The future is bright! Integrating ketone sensing into Continuous Glucose Monitors (CGM) will create dual-analyte continuous sensors. This will revolutionize glucose and ketone monitoring.

References

  1. Electrochemical sensors for ketone bodies: A reviewSource

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